We set out to investigate the potential of garlic derivatives as an alternative treatment for ear infections. With antibiotic resistance on the rise, finding new ways to combat these infections has become increasingly crucial.
Our study focused on the antimicrobial properties of four garlic compounds: allicin, s-allyl cysteine (SAC), diallyl disulfide (DADS), and s-allyl mercaptocysteine (SAMC). By using the broth microdilution method, we tested how effectively these compounds could inhibit the growth of bacteria and yeasts that commonly cause ear infections.
We were excited to find that both allicin and SAC demonstrated impressive antimicrobial activity, even at low concentrations. This opens up the possibility that these garlic derivatives could be used in the future to treat infections in the ear. However, DADS and SAMC showed considerably less effectiveness, particularly SAMC, which did not showcase any significant impact against the tested microorganisms.
Overall, our findings suggest that garlic derivatives, particularly allicin and SAC, could represent a promising direction in the search for new treatments for ear infections.